|
|
|
| Registros recuperados: 47 | |
|
| |
|
| |
|
| |
|
| |
|
|
| Ben Henda, Yesmine; Laamari, Mariem; Lanneluc, Isabelle; Travers, Marie-agnes; Agogue, Helene; Arnaudin, Ingrid; Bridiau, Nicolas; Maugard, Thierry; Piot, Jean-marie; Sannier, Frederic; Bordenave-juchereau, Stephanie. |
| The effect of 11 marine-derived cryptides was investigated on proliferation, differentiation and maturation of human white pre-adipocytes (HWP). They were all formerly identified as potent Angiotensin-Converting-Enzyme inhibitors.Val-Trp (VW),Val-Tyr (VY), Lys-Tyr (KY), Lys-Trp (KW), Ile-Tyr (IY), Ala-Pro (AP),Val-Ile-Tyr (VIY), Leu-Lys-Pro (LKP), Gly-Pro-Leu (GPL), Ala-Lys-Lys (AKK) and Val-Ala-Pro (VAP) were previously found in fish products and coproducts as well as other marine resources like wakame. Treatment with AP, VAP and AKK greatly affected viability of HWP during the proliferation period while KW and VW treatment reduced the number of viable cells during the differentiation stage. A GPL and IY incubation during the differentiation stage allowed... |
| Tipo: Text |
Palavras-chave: Bioactive peptides; Obesity; Human white pre-adipocytes'; Proliferation; Differentiation; Adipocyte differentiation markers. |
| Ano: 2015 |
URL: http://archimer.ifremer.fr/doc/00269/38014/36308.pdf |
| |
|
|
| Wu, Chuan-fen; Delsert, Claude; Faure, Sandrine; Traverso, Edwin E.; Kloc, Malgorzata; Kuang, Jian; Etkin, Laurence D.; Morin, Nathalie. |
| Tumorhead (TH) regulates neural plate cell proliferation during Xenopus early development, and gain or loss of function prevents neural differentiation. TH shuttles between the nuclear and cytoplasmic/cortical cell compartments in embryonic cells. In this study, we show that subcellular distribution of TH is important for its functions. Targeting TH to the cell cortex/membrane potentiates a TH gain of function phenotype and results in neural plate expansion and inhibition of neuronal differentiation. We have found that TH subcellular localization is regulated, and that its shuttling between the nucleus and the cell cortex/cytoplasm is controlled by the catalytic activity of p21-activated kinase, X-PAK1. The phenotypes of embryos that lack, or have excess,... |
| Tipo: Text |
Palavras-chave: Actin cytoskeleton; Differentiation; Proliferation; Neural plate; P21 activated kinase; Tumorhead. |
| Ano: 2007 |
URL: http://archimer.ifremer.fr/doc/2007/publication-2996.pdf |
| |
|
|
| Barrat, Jean-alix; Ferrière, L.. |
| Main-group pallasites (MGPs) are meteorites mainly composed of Fe-Ni metal and olivines, the latter being considered as one of the largest sampling of extraterrestrial mantle material available for study on Earth. We analysed the rare earth element (REE) concentrations of olivines from six MGPs to understand better the processes of formation of their parent mantle. All the investigated samples display very low REE abundances, and enrichments in both light REEs and heavy REEs. We interpret the light REE enrichments as a fingerprint of terrestrial contamination. The least contaminated olivines have higher heavy REE enrichments than those inferred for olivines directly crystallised in a magma ocean. Such enrichments in heavy REEs are possible if the mantle of... |
| Tipo: Text |
Palavras-chave: Pallasite; Early solar system; Trace elements; Rare earth elements; Differentiation. |
| Ano: 2021 |
URL: https://archimer.ifremer.fr/doc/00686/79770/82569.pdf |
| |
|
| |
|
|
| Alibardi,Lorenzo. |
| The present ultrastructural study on developing and regenerating feathers of chick and zebrafinch describes the ultrastructural changes that occur during the differentiation of barb cells that leads to the formation of the ramus of barbs. Differently from barbule and barb cortical cells that accumulate feather keratin, barb medullary cells undergo to lipid degeneration. Eventually, lipids disappear and medullary cells become empty cavities in the central part of the ramus. In barb medullary cells feather keratin is accumulated in few peripheral bundles that merge with those of cortical cells to fom the wall of the ramus. The latter is joined with branching barbules. The process that controls the transition from keratin-synthesizing to lipid-producing barb... |
| Tipo: Journal article |
Palavras-chave: Feathers; Barbs; Differentiation; Lipidization; Ultrastructure. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000100010 |
| |
|
| |
|
| |
|
|
| Heiman, Amir; Ofir, Chezy. |
| This paper analyzes the effect of competition on product demonstration decisions. Pre-purchase product demonstration enables marketers to differentiate products that are ex-post differentiated but are judged according to perceived fit, rather than actual fit, due to pre-purchase consumer uncertainty. Imbalanced competition accompanied by fit uncertainty motivates the follower to offer demonstrations to avoid a price war. This paper explores the conditions that lead the leader to retaliate. In addition to effects on quantity, competition may increase the quality of demonstrations offered by the leader. We analyze a business case, showing that competition may increase the demonstration intensity and that the leading manufacturer’s response to changes in... |
| Tipo: Working or Discussion Paper |
Palavras-chave: Imbalanced competition; Product demonstration; Differentiation; Test-drive; Price war; Political Economy; Production Economics. |
| Ano: 2010 |
URL: http://purl.umn.edu/93131 |
| |
|
|
| Barrena Figueroa, Ramo; Sanchez Garcia, Mercedes. |
| Due to a high level of product substitution in the food market, it often proves difficult to strike a balance between supply and demand. This is especially true in sectors with a such high level of competition and product differentiation as the wine producing sector. Faced with the difficulty of differentiating the product in terms of its technical characteristics, quality and price, therefore, a useful alternative is to explore what consumers perceive to be its "emotional benefits", since these have been shown to have a decisive effect on consumer purchasing decisions. For marketing purposes, an understanding of how consumers' personality traits condition their choice of products can help manufacturers to improve their strategic positioning in the market.... |
| Tipo: Conference Paper or Presentation |
Palavras-chave: Wine; Consumer behaviour; Laddering; Emotions; Differentiation; Demand and Price Analysis. |
| Ano: 2007 |
URL: http://purl.umn.edu/9435 |
| |
|
|
| Chambolle, Claire; Villas-Boas, Sofia Berto. |
| This paper shows that retailers may choose to offer products differentiated in quality to consumers, not to relax downstream competition, but to improve their buyer power in the negotiation with their supplier. We consider a simple vertical industry where two producers sell products differentiated in quality to two retailers who operate in separated markets. In the game, first retailers choose which product to carry, then each retailer and her chosen producer bargain over the terms of a two-part tariff contract and retailers finally choose the quantities. When upstream production costs are convex, the share of the total profits going to the retailer would be higher if they choose to differentiate. We thus isolate the wish to differentiate as "only" due to... |
| Tipo: Working or Discussion Paper |
Palavras-chave: Buyer Power; Product line; Differentiation; Marketing; L13; L42. |
| Ano: 2007 |
URL: http://purl.umn.edu/6866 |
| |
|
| |
|
|
| Monterio, G.F.A.; Farina, Elizabeth Maria Mercier Querido; Nunes, R.. |
| The paper analyzes competition among supermarkets in Brazil. In contrast to part of the economic literature which suggests that the fast growth of big supermarket chains would destroy independent, medium and small supermarkets, the paper argues that big supermarket chains can coexist with different formats of independent food retailing. As a result, competition in food retail is complex and cannot be described as a simple Darwinian process of market concentration. The analysis is divided in two parts. In the first part, the competition between hypermarkets and supermarkets is examined. Evidences for the district of Sao Paulo, Brazil, suggest that these retailers form separate markets. The second part is focused on neighborhood supermarkets. The results... |
| Tipo: Conference Paper or Presentation |
Palavras-chave: Food retail; Supermarkets; Differentiation; Agribusiness; Industrial Organization. |
| Ano: 2008 |
URL: http://purl.umn.edu/44199 |
| |
|
| |
|
| |
|
|
| Fan,Caiyun; Zhang,Yunhai; Wang,Juhua; Cheng,Jianbo. |
| ABSTRACT This study examined the effects of purmorphamine and cyclopamine, classical agonists and inhibitors of the Hedgehog (Hh) signaling pathway, in the adipogenic differentiation of porcine adipose-derived mesenchymal stem cells (AMSC) to investigate the roles underlying adipogenic differentiation in AMSC. Porcine-derived AMSC were established, and the Hh signaling pathway was activated or inhibited by treatment with purmorphamine or cyclopamine. The adipogenic differentiation of the porcine AMSC was then analyzed by Oil Red O staining. The expression levels of Hh signaling pathway factors and adipogenic transcription factors were determined using quantitative real-time polymerase chain reaction and western blot analysis. We verified that the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adipogenesis; Differentiation; Expression; Pig. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982018000100415 |
| |
|
|
| Barcellos,Júlio Otávio Jardim; Abicht,Alexandre de Melo; Brandão,Fernanda Scharnberg; Canozzi,Maria Eugênia Andrighetto; Collares,Fernando Carbonari. |
| The objective of this study was to determine consumers understanding of beef traceability, identifying how consumers value this meat and traceability elements to be presented on retail shelves. The method used in this study was a survey through the internet applying the Sphinx software. The sample consisted of 417 consumers, mostly living in Porto Alegre, Brazil. Consumers are aware of certified beef, consider it important, but this is not a demand. As to traced beef, most consumers (62.4%) are in favor of mandatory traceability of beef cattle in Brazil, but 86.6% disagree with the destination of traced beef only to the foreign market. The majority of people are willing to pay more for traced beef and consider traceability a market opportunity, used as a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Agribusiness; Certification; Differentiation; Quality; Traceability. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982012000300041 |
| |
| Registros recuperados: 47 | |
|
|
|
